Taking FYCOMPA®

FYCOMPA: One dose, every night, at bedtime

  • FYCOMPA comes in tablet or liquid form
  • FYCOMPA tablets should be swallowed whole with water
  • Your FYCOMPA dose may start at 2 mg (4 mL liquid) or 4 mg (8 mL liquid) depending on the other seizure medicines you are taking
  • Your doctor may slowly raise your dose by 2 mg (4 mL) at a time. This is so you get the dose that works for you
  • Do not change your dose without first talking to your doctor
  • If you take more FYCOMPA than you are supposed to, call your local Poison Control Center or go to the nearest hospital emergency room right away
  • Please see the Medication Guide for more detailed instructions on dosing

Liquid is available as 0.5 mg/mL.


FYCOMPA comes in
different doses

Dose visuals are not actual size or amount.

How to take FYCOMPA liquid

Step 1. Remove the FYCOMPA liquid bottle, adapter, and 2 syringes from the box.

Step 2. Shake the bottle well before each use.

Step 3. Uncap the bottle. Insert the adapter into the bottle. It will stay there until the bottle is empty.

FYCOMPA Liquid Bottle Adapter

Step 4. Find your dose (in milliliters [mL]) on the syringe.

FYCOMPA Liquid Dose Diagram

Step 5. Put the syringe in the upright bottle. Push the plunger all the way down.

FYCOMPA Syringe In Bottle

Step 6. With the syringe in place, turn the bottle upside down. Pull the plunger to the number of mL needed (the amount of liquid medicine in Step 4). If you see air bubbles in the oral syringe, fully push in the plunger so that the liquid medicine flows back into the bottle. Then, withdraw your prescribed dose of liquid medicine. Measure from the white layer at the end of the plunger, not the black layer.

FYCOMPA Syringe in Upside Down Bottle

Step 7. If the dose is more than 20 mL, you can use 2 syringes. Or you can use 1 syringe twice by repeating the steps above.

Step 8. Remove the syringe from the adapter.

Step 9. Slowly squirt FYCOMPA directly into the corner of your mouth.

Liquid FYCOMPA Oral Administration Diagram

Step 10. Rinse the syringe (or syringes) with tap water after each use.

Cleaning FYCOMPA Syringe After Dosing

Step 11. Cap the bottle tightly. The cap will fit over the adapter. Use within 90 days of first opening bottle.

Store at room temperature. Do not store above 86°F. Do not freeze.

Please read the Medication Guide, including the information about serious mental (psychiatric) problems, at the end of the Prescribing Information. The Medication Guide does not take the place of talking with your healthcare provider about your condition or your treatment.

NEXT: LEARN ABOUT SEIZURE TYPES

Indication and Important Safety Information

Important Safety Information

FYCOMPA may cause mental (psychiatric) problems, including: new or worse aggressive behavior (including homicidal behavior), hostility, anger, anxiety, or irritability; being suspicious or distrustful (believing things that are not true); seeing objects or hearing things that are not there; confusion; difficulty with memory; other unusual or extreme changes in behavior or mood. Tell your healthcare provider right away if you have any new or worsening mental problems while taking FYCOMPA.

FYCOMPA is a prescription medicine used in people with epilepsy aged 12 and older alone or with other medicines to treat partial-onset seizures with or without secondarily generalized seizures and with other medicines to treat primary generalized tonic-clonic seizures

Pay attention to any changes especially sudden changes in mood, behaviors, thoughts, or feelings and keep all follow-up visits with your healthcare provider as scheduled. Call your healthcare provider between visits as needed, especially if you are worried about symptoms.

Do not stop FYCOMPA without first talking with your healthcare provider. Stopping suddenly can cause serious problems and can cause you to have seizures more often.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking FYCOMPA with certain other medicines can cause side effects or reduce either drug’s benefit. These medicines include: birth control, carbamazepine, phenytoin, oxcarbazepine, rifampin, and St. John’s Wort.

What should I avoid while taking FYCOMPA?
Do not drive, operate heavy machinery, or do other dangerous activities until you know how FYCOMPA affects you. FYCOMPA may make you dizzy, sleepy, or tired. Do not drink alcohol or take other medicines that make you sleepy or dizzy until you talk to your healthcare provider. FYCOMPA taken with alcohol or medicines that cause sleepiness or dizziness may make your sleepiness or dizziness worse. FYCOMPA when taken with alcohol may also make your mood worse, increase anger, confusion, and depression.

FYCOMPA may cause other serious side effects, including: Dizziness, vertigo (sense of spinning), and problems walking normally. You may have problems walking normally if you are unsteady because you feel dizzy. These symptoms can increase when your dose of FYCOMPA is increased. Your risk of feeling dizzy and having problems walking normally may be higher if you are elderly; Sleepiness and tiredness; Increased risk of falls. Taking FYCOMPA can increase your chance of falling. These falls can cause serious injuries. Your risk of falling may be higher if you are elderly; A serious allergic reaction that may affect your skin or other parts of your body such as your liver, kidneys, heart, or blood cells. This allergic reaction can be life-threatening and can cause death. Call your healthcare provider right away if you have: a skin rash, hives; fever or swollen glands that do not go away; swelling of your face; shortness of breath; swelling of the legs; yellowing of the skin or whites of the eyes; or dark urine

The most common side effects of FYCOMPA include: dizziness; sleepiness; tiredness; irritability; falls; nausea and vomiting; weight gain; vertigo (sense of spinning); problems walking normally; problems with muscle coordination; headache; bruising; abdominal pain; anxiety

FYCOMPA is a controlled substance (CIII) because it can be abused or lead to drug dependence. Keep FYCOMPA in a safe place to protect it from theft and never give it to anyone else because it may harm them. Selling or giving away FYCOMPA is against the law.

Prescribing Information and Medication Guide for FYCOMPA.